Endocrine Abstracts

Introduction: Gestational diabetes mellitus (GDM) is a common metabolic disorder. The risk factors for GDM are often employed in selective screening. The impact of risk factors for GDM on newborn is yet to be fully evaluated.Objective: To determine the impact of maternal clinical risk factors for gestational diabetes mellitus on the anthropometric and clinical outcomes of the newborns.Method: The study was a prospective open cohort...

Introduction: Turner Syndrome (TS) is the most common chromosomal abnormality affecting phenotypic females. Short stature (SS) is one of the most consistent clinical features of TS, with consequent poor psychosocial outcomes. Management involves early diagnosis and administration of recombinant human growth hormone (rhGH). The cost of therapy however hampers treatment in resource-challenged regions. The objective of this presentation is to report the outcome and challenges of ...

Introduction: Hypopituitarism refers to deficiency of one or more of the pituitary hormones. Hypopituitarism is often partial, thus replacement is individualized. Hormonal replacement improves quality of life in these patients.Objective: To describe the demographic characteristics and patterns of hormonal replacement in patients with hypopituitarism attending the Endocrinology clinic of a tertiary hospital in Lagos, Nigeria.Methods...

Introduction: Primary hyperparathyroidism is a common endocrine disorder. Symptoms at onset are often non-specific, thus the diagnosis tends to be overlooked.Objective: To highlight varying modes of presentation in primary hyperparathyroidism, the need for early recognition and treatment to prevent complications.Case Presentation: A 51-year old woman presented with complaints of back and lower limb pains of 7-year duration. She als...

Background: Quantifying the body fat percentage (%BF), its scientific and clinical implications is critical to timely intervention as it has been proven to be a better measure of patient’s risk of cardiovascular diseases than the BMI. Several techniques have been developed to assess BF including imaging, DEXA, bioelectric impedance analysis (BIA), and underwater weighing. The use of anthropometric indices to derive %BF provides an inexpensive surrogate. There are very few...

Background: Besides differences in the overall prevalence between IGT and IFG, there is now clear evidence of differences in phenotype between the two categories. The most consistent and statistically significant difference is that IFG is commoner in men than women in virtually all age groups, typically being 1.5–3 times higher, but up to seven or eight times higher in Europeans aged 50–70 years. Conversely, the prevalence of IGT is higher in women than men in all ag...

Objectives: Obesity is a risk factor for Type 2 diabetes mellitus. This study evaluated the relationship between central obesity and fasting plasma glucose (FPG).Materials and methods: A cross-sectional study involving five hundred and twenty one (521) adult participants (134 males and 387 females) of a community health survey in Sagamu, Isara and Ode-Remo, Nigeria. The waist circumference (WC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) o...

Background: There is a relationship between the indices of nutriture-BMI, waist circumference (WC), waist–hip ratio (WHR) and the development of glucose intolerance.Objectives: To determine the normative values of the indices of nutriture and the inter relationship between these indices in male and female residents of a Calabar, South East Nigeria.Methods: A sample comprising 1134 subjects (645 males and 489 females) represent...

Objectives: To determine the mean and normative values of anthropometry among the inhabitants of a coastal Nigerian city.Methods: A cross sectional survey comprising 1134 subjects (645 males and 489 females) representative of the entire population of Calabar metropolis aged 15–79 was studied. A multistage sampling method was applied to select the subjects. Using a modification of WHO STEPS instrument the information obtained included anthropometric ...

Introduction: Major risk factors for cardiovascular disease and outcome include, though not limited to, hypertension, diabetes mellitus and obesity. In the wake of present urbanization, the prevalence of these risk factors has increased, impacting greatly on disease burden.Objectives: To determine the prevalence of undiagnosed Diabetes, Hypertension, Obesity and associated demographic factors in a market population in La...